Materiais Nanoteranósticos de Carbono: Pontos Quânticos de Carbono e Carbonos Mesoporosos Ordenados

Autores

  • Larissa Silva de Olveira Mota BioCrom, Laboratório de Cromatografia de Bioafinidade e Química Ambiental, Instituto de Química, Universidade Federal Fluminense - UFF, Niterói, RJ, Brasil https://orcid.org/0000-0001-9525-8730
  • Bruno Salarini Peixoto BioCrom, Laboratório de Cromatografia de Bioafinidade e Química Ambiental, Instituto de Química, Universidade Federal Fluminense - UFF, Niterói, RJ, Brasil https://orcid.org/0000-0002-9091-525X
  • Larissa de Souza Santana Mestrado Profissional em Ciência e Tecnologia Farmacêutica, Faculdade de Farmácia, Universidade Federal do Rio de Janeiro - UFRJ https://orcid.org/0000-0003-2224-8464
  • Luiz Claudio Rodrigues Pereira da Silva Laboratório de Nanoteranósticos, Faculdade de Farmácia, Universidade Federal do Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, Brasil https://orcid.org/0000-0002-6746-5756
  • Marcela Cristina de Moraes Universidade Federal Fluminense https://orcid.org/0000-0001-7448-5301

DOI:

https://doi.org/10.21577/1984-6835.20220099

Resumo

Ordered mesoporous carbon nanoparticles (OMCNs) and carbon dots (C-dots) are emerging materials that have shown great potential for application in the biomedical field, biocompatibility, and versatility in the delivery of therapeutic and as diagnostic agents. There is still a great potential to be explored as nanotheranostic systems due to the simultaneous emission of heat and fluorescence by C-dots and photoacoustic and photothermal imaging of OMCNs. In the present work, we review the main advances in the use of these materials for drug delivery, mostly for treating tumors, highlighting an overview of methods of synthesis and conjugation to molecules, the responsiveness to endogenous and exogenous stimuli, the use in diagnostic imaging techniques, and an analysis of intellectual property in the last decade.

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Publicado

01-03-2023