Plantas Brasileiras com Efeito Inibitório in vitro sobre a alfa-Glicosidase

Resumo

This study gathered experimental data regarding the evaluation of the inhibitory capacity of α-glycosidase
in Brazilian plants, available in scientific articles found in the Scopus, Science Direct Journals, Scielo, and
Google Academic databases during the period from 2010 to 2021. This included 82 species distributed
across 29 families, with Myrtaceae being the most investigated in Brazil. The article only discusses
experimental in vitro studies on natural products (chemical components and extracts) from Brazilian
plants. Therefore, casual or popular medicine studies were not cited. The strategy used showed evident
potential for genera and species that commonly occur in Brazilian biomes to act as therapeutic agents
for diabetes mellitus, although there were few articles about α-glycosidase published in the databases.
Myrcia species stand out because of the numerous citations that evaluate the enzyme, as well as the many
metabolites identified in the species that show greater potential than the standard. However, although these
plants are described in traditional medicine as treatment for diabetes mellitus, and despite showing some
effectiveness in inhibiting the enzyme, further studies are still required for more definitive conclusions,
as well as technical clarifications regarding purpose, preparation, and use.